Fantasy Football Week 4: Key Start/Sit Decisions to Make

PHILADELPHIA, Pa. — In Week 4 of the NFL season, fantasy football managers are grappling with important start/sit decisions as they prepare their lineups. Notable players are facing injuries, tough matchups, and emerging statistics that could influence weekly performance.

One player to watch is Seattle Seahawks’ Jaxon Smith-Njigba, who ranks WR4 in targets per game and has earned significant first-read targets. Meanwhile, Trey McBride is expected to benefit from the Seahawks’ zone-heavy defensive approach, potentially leading to increased targets.

For the Arizona Cardinals, running back Trey Benson is stepping into a lead role following James Conner‘s season-ending injury. Although Benson’s usage is promising, he faces a challenging matchup against the Seahawks, who have a strong run defense.

Quarterback Kyler Murray is also making headlines as he averages over six carries per game, potentially increasing his rushing stats against a vulnerable spot in Seattle’s defense.

In contrast, Marvin Harrison, the Cardinals’ wide receiver, has been struggling to maintain target volume, often being overshadowed by McBride’s increasing relevance in the passing game.

The Vikings’ wide receiver Justin Jefferson, meanwhile, is adapting to the team’s game plan as they limit passing attempts, making him a lower-end WR2 this week against Green Bay.

As for tight ends, T.J. Hockenson is showing solid numbers, especially against defenses that struggle to contain the position, like Pittsburgh’s.

In other matchups, injuries are reshaping expectations. Chicago’s DJ Moore is dropping off in target share, while Dallas’ CeeDee Lamb will miss the game due to injury, making it difficult for quarterback Dak Prescott to find consistent targets.

In summary, Week 4 promises to be a critical one for fantasy managers, requiring close attention to injuries and matchup statistics to optimize their lineups.