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49ers Eye Key Draft Picks to Strengthen Roster Ahead of 2025 NFL Draft

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Nfl Draft San Francisco 49ers Predictions

SAN FRANCISCO, Calif. — With just over two weeks until the 2025 NFL Draft, analysts are honing in on potential selections for the San Francisco 49ers, focusing on bolstering the offensive and defensive lines or secondary. The team is navigating a roster reshaped by key departures in free agency, particularly along both lines, prompting many to emphasize priorities for their first-round pick.

Several draft experts predict the 49ers could select high-impact players capable of providing immediate reinforcement. Analysts have highlighted a range of prospects who may fit the team’s needs, considering recent roster shifts and performance metrics.

One preferred choice for the 49ers is Will Campbell, projected to enhance their offensive line. An analyst noted, “The 49ers add Campbell’s strength and pass protection skills at left guard, with the chance he eventually takes over one of the tackle spots.”

Others suggest focusing on interior defense, with a preference for powerful linemen. A recent analysis stated, “Drafting a tough, physical player who can create disruption from the interior should be a huge priority.”

For defensive needs, prospects like Walter Nolen are mentioned as ideal fits. One expert described, “Nolen would be a play-wrecker for them. He is overwhelmingly powerful and explosive and could help replace veterans like Maliek Collins and Javon Hargrave,” following a strong showing at Ole Miss with 6.5 sacks in a single season.

The secondary also emerges as a focal point, notably after Charvarius Ward‘s departure in free agency. Analysts suggest investing in versatile cornerbacks like Jahdae Barron, who recorded an 82.0 PFF coverage grade last year. An expert highlighted, “Barron is a versatile cornerback who would excel in Robert Saleh‘s quarters-heavy scheme.”

As the 49ers prepare for the draft, the organization continues to assess player capabilities and fit within their defensive strategies. The coming weeks will prove pivotal for San Francisco’s efforts to enhance their roster for the 2025 season.

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