NFL Week 10 Preview: Key Matchups and Predictions

JACKSONVILLE, Fla. — The 2025 NFL Week 10 schedule features exciting matchups as teams push for playoff spots. Major games include the Colts facing the Falcons in Berlin and the Eagles against the Packers at Lambeau Field.

The Colts, coming off a disappointing loss, are trading for cornerback Sauce Gardner to bolster their defense against the Falcons. Meanwhile, the Falcons’ defense ranks among the league’s best, but has been vulnerable against the run. Coach Raheem Morris noted, “You need to bring a lot of people to tackle,” when discussing their upcoming matchup.

In Minnesota, the Eagles will look for a bounce-back performance after their Week 9 bye. The Eagles, who are tied for the fewest turnovers this season, will rely on their strong offensive line to counter the Packers’ pass rush. Coach Nick Sirianni emphasized the need for a streamlined passing game.

Additionally, the Ravens visit the Vikings in a game pivotal for both teams’ playoff hopes. Ravens quarterback Lamar Jackson boasts a stellar record against NFC teams, and their defense has relaxed into a rhythm, allowing only one passing touchdown in the last three games.

The day will kick off with the managed game between the Jaguars and Texans, where Jacksonville will be without key receivers due to injuries. Coach Liam Coen acknowledged the challenge, saying, “We have to make some dirty, grimy, contested plays.”

As excitement builds for this week’s matchups, fantasy managers should note the injuries affecting starters. Bills quarterback Josh Allen aims to maintain his strong performance against the Dolphins, while Buccaneers receiver Tez Johnson could have a standout game against the Patriots.

Each of these matchups carries weight as teams are desperate for wins heading into the later part of the season. Coaches and players alike are preparing for what could shape their postseason prospects.