Brissett’s Record-Setting Performance Can’t Save Cardinals from Loss

Canton, OH — Arizona Cardinals quarterback Jacoby Brissett made history in a crushing defeat against the San Francisco 49ers on November 20, 2025. Despite setting an NFL single-game record by completing 47 passes, the Cardinals lost 41-22 in Week 11.

Brissett’s impressive performance came amid a challenging game, as the Cardinals were compelled to throw the ball 57 times due to their defense’s struggles. The team found itself playing catch-up throughout the match, ultimately scoring only 22 points. Brissett’s record included two interceptions, a statistic that has led to mixed reactions among fans.

This record-breaking achievement places Brissett in the company of Drew Bledsoe and Jared Goff, who previously completed 45 passes in their respective games. Brissett, who stepped in as the starting quarterback after Kyler Murray‘s injury, has been under tremendous pressure during his tenure, as the Cardinals hold a 1-4 record since he took the helm.

Brissett’s statistics for the season include a completion rate of 66.98% and an average of 7.41 yards per attempt. Over five starts, he has thrown for 1,570 yards and scored 11 total touchdowns. However, the recent loss has overshadowed these accomplishments.

Fans expressed frustration on social media, with some commenting on the significance of the record in light of the loss. One user pointedly remarked, “Still lost by 20,” reflecting the disappointment felt by many within the fan base. Others questioned the honor of displaying Brissett’s jersey at the Pro Football Hall of Fame since it came from a losing effort.

Despite the negative sentiment, Brissett’s performance will not be forgotten easily, as he prepares to lead the Cardinals into their next game in Week 12.