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Final Interview of Tylenol Murders Suspect Raises New Questions

CHICAGO, Ill. — James Lewis, the prime suspect in the infamous 1982 Tylenol poisonings, recently gave his final interview in a Netflix docuseries titled “Cold Case: The Tylenol Murders.” This interview comes nearly 41 years after the tragic deaths of seven individuals who ingested cyanide-laced Tylenol in the Chicago area. The killings sparked widespread panic and led to significant changes in packaging regulations for over-the-counter medications.
Between September 29 and October 1, 1982, victims, including a 12-year-old girl, died after consuming the tainted capsules. This incident prompted a nationwide recall of Tylenol products and increased scrutiny into consumer safety. The case remains unsolved and continues to intrigue both the public and law enforcement.
In his interview, Lewis attempted to clear his name, claiming he was framed. Director Yotam Guendelman noted that during filming, Lewis exhibited varying emotions that made the crew uneasy. “We caught him in a few lies, and then he snapped for a couple of minutes,” Guendelman said. “It became really scary.”
Lewis, who passed away in July 2023 at age 76, had long denied involvement in the poisonings. In 2010, he provided DNA samples to the FBI and described efforts to exonerate himself, including creating a website claiming innocence. He asserted that, at the time of the poisonings, he and his wife were in New York City.
According to reports, investigators believe the killer obtained Extra-Strength Tylenol from various stores, lacing the capsules with lethal doses of potassium cyanide before placing them back on store shelves. Lewis, previously involved in criminal activities, was convicted of extortion in connection with the case and spent over a decade in prison.
Director Ari Pines expressed surprise at Lewis’s willingness to participate in the interview. “He loved the attention. We built trust with him slowly over time, which helped us get the story he had to tell,” Pines explained.
Lewis’s troubled past includes previous charges related to a murder case from 1978 and a mail fraud conviction in 1981. Despite a long history of legal issues, the FBI could never definitively link him to the Tylenol poisonings.
In the Netflix series, loved ones of the victims shared their theories about the possible motives behind the poisonings, including potential revenge against Johnson & Johnson, the parent company of Tylenol. The series also raises questions about other suspects who might still be at large and the possibility of more undiscovered victims.
The investigative team hopes that unsealing previously sealed documents could shed new light on the case. “The truth is out there, and there’s someone out there who knows more,” Pines stated. “I hope that person will see this film and come forward.”