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Padres Face Phillies in Key MLB Series Opener Tonight

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San Diego Padres Vs Philadelphia Phillies June 2025

Philadelphia, PA — The San Diego Padres will take on the Philadelphia Phillies at Citizens Bank Park tonight at 6:30 p.m. ET. This matchup marks the beginning of a three-game series.

The Padres, who currently hold a record of 45-38, are looking to turn their recent fortunes around after losing two of their last three games. San Diego has a modest plus-17 run differential for the season, but they have struggled on the road with a record of 20-24.

The Phillies, with a record of 49-35, are coming off a win against the Atlanta Braves and have won two of their last three games. This season, they boast a strong plus-46 run differential and an impressive 26-14 record at home.

In tonight’s game, the Phillies are favored at -226 on the money line, meaning a bet of $226 would yield a profit of $100. The over/under for total runs is set at 9 by sportsbooks.

Right-hander Zack Wheeler is scheduled to start for Philadelphia with a record of 7-3 and an impressive 2.45 ERA. He has struck out 126 batters in 99 innings pitched this season. Wheeler aims to build on his recent performance, having allowed only two earned runs in four starts during June.

The Padres will counter with Matt Waldron, who is making his season debut. Waldron went 7-11 with a 4.91 ERA in 2024 and will face a formidable Phillies lineup tonight.

Shortstop Trea Turner has been a standout for Philadelphia, hitting .296 with 11 home runs and 37 RBIs this season. In a recent game against the Braves, he contributed significantly to their offensive push.

Meanwhile, the Padres are relying on third baseman Manny Machado, who has contributed 13 home runs and 47 RBIs this season. In previous matchups against the Phillies, Machado has demonstrated a strong ability to deliver key hits.

Tonight’s game is crucial for both teams as they seek to secure their place in the playoff race. As Philadelphia leads the NL East and the Padres look to close the gap in the NL West, stakes are high. Tune in for what promises to be an exciting series opener.